Incidental Findings of Variant Hemoglobin During Hemoglobin A1cTesting
نویسندگان
چکیده
منابع مشابه
Incidental findings of variant hemoglobin during hemoglobin A(1c) testing.
A variant hemoglobin fraction may be an incidental finding during HbA(1c) analysis using the G8 Tosoh HPLC analyzer, but it is unclear if the retention times and fraction patterns can reliably predict the findings of a high-performance liquid chromatography (HPLC) β-thalassemia program (Bio Rad Variant II analyzer). We chose 100 samples sent for HbA(1c) determinations (G8 Tosoh) with an inciden...
متن کاملHemoglobin Variant (Hemoglobin Aalborg) Mimicking Interstitial Pulmonary Disease
Hemoglobin Aalborg is a moderately unstable hemoglobin variant with no affiliation to serious hematological abnormality or major clinical symptoms under normal circumstances. Our index person was a healthy woman of 58, not previously diagnosed with hemoglobinopathy Aalborg, who developed acute respiratory failure after a routine cholecystectomy. Initially she was suspected of idiopathic interst...
متن کاملSite-specific semisynthetic variant of human hemoglobin.
A single round of Edman degradation was employed to remove the NH2-terminal valine from isolated alpha chains of human hemoglobin. Reconstitution of normal beta chains with truncated or substituted alpha chains was used to form truncated (des-Val1-alpha 1) and substituted ([[1-13C]Gly1]alpha 1) tetrameric hemoglobin analogs. Structural homology of the analogs with untreated native hemoglobin wa...
متن کاملDelta beta thalassemia: a rare hemoglobin variant
Abbreviations: CBC, complete blood count; Hb, hemoglobin; HPLC, high-performance liquid chromatography. 2011;26:162-5. 7. Cho HY, Lee BS, Moon KC, Ha IS, Cheong HI, Choi Y. Complete factor H deficiency-associated atypical hemolytic uremic syndrome in a neonate. Pediatr Nephrol 2007;22:874-80. 8. Frémeaux-Bacchi V, Miller EC, Liszewski MK, et al. Mutations in complement C3 predispose to developm...
متن کاملHemoglobin NYU , a Delta Chain Variant
A minor hemoglobin (Hb) component with the electrophoretic properties of the 8-chain variant Hb A2' was encountered in two unrelated families of Russian-Jewish ancestry. This minor component, designated Hb NYU, was shown to result from the substitution of lysine for asparagine at 8'. We have confirmed studies of others that hemoglobin A2' isolated from the hemoglobin of some African subjects, r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2012
ISSN: 0002-9173,1943-7722
DOI: 10.1309/ajcpj0gsrwf0ubyt